Elinye lamasonto abalulekile eLisbon yilelo le USanta Anthony (Igreja de Santo António de Lisboa) enikezelwe kuSanta Anthony waseLisbon, owaziwa kangcono emhlabeni wonke wamaKristu njengoSanta Anthony wasePadua. Ngokwesiko, isonto lakhiwa endaweni lapho kuzalwa khona usanta, ngo-1195.
Umlando ulandisa ukuthi uFernando de Bulhões, uSanta Anthony, wazalelwa eLisbon ngo-1195, indodana yomndeni ocebile. Ngo-1220, ngenkathi efunda eCoimbra, wangena kwi-Order of Franciscan, esebenzisa igama lika-Antonio. Uhambo lwakhe lwezithunywa zevangeli lwaluzomyisa e-Italy, lapho azinza khona ePadua. Ngenxa yokuthandwa kwakhe okukhulu, wabekwa njengogunyaziwe ngaphansi konyaka ngemuva kokushona kwakhe, ngo-1232.
Isiza sekhaya lomndeni lapho uFernando azalelwa khona, esiseduze kakhulu neLisbon Cathedral, saphendulwa isonto elincane ngekhulu le-15. Lesi sakhiwo sokuqala, esingasali lutho, sakhiwa kabusha ngekhulu le-16, ngesikhathi sokubusa INkosi uManuel I.
Ngo-1730, ngaphansi kokubusa kukaJohn V, isonto laphinde lakhiwa futhi lahlelwa kabusha. Ekuzamazameni komhlaba kwaseLisbon ngo-1755 isonto laseSanto António labhujiswa, futhi yindlu enkulu yesonto kuphela eyayimi. Yakhiwa kabusha ngokuphelele ngemuva kuka-1767 kuya kumklamo weBaroque-Rococo ngumdwebi uMateus Vicente de Oliveira. Leli isonto elingavakashelwa namuhla.
Kusukela ngo-1755 udwendwe luphuma esontweni njalo ngoJuni 13, ludlule eLisbon Cathedral futhi lidlule emithambekeni yendawo yase-Alfama, endaweni eseduze.
Kumele kuqashelwe ukuthi ngoMeyi 12, 1982, uPapa John Paul II wavakashela isonto. Ngemuva kwalokho kwavulwa isifanekiso sikaSanta Anthony (ngumdwebi wezithombe uSoares Branco) esigcawini esiphambi kwesonto sathandaza ku-crypt, ekhomba indawo lapho kuzalwa khona usanta.
